Flavofort 1500®

Linea Flavofort 1500

Flavofort 1500<sup>®</sup>
30 tablets

Flavofort 1500®

Food supplement in tablets and in sachets based on micronised flavonoids, Centella, blueberry, red grapevine and vitamin C useful to improve microcirculation functions (and results on hemorrhoids, too)
Flavofort 1500® is a food supplement based on micronized Flavonoids, Plant Extracts and Vitamin C useful in case of reduced intake or increased need for these nutrients. Blackberry, Centella and Red grapevine are useful for the microcirculation function, reducing the feeling of heaviness in the legs. Vitamin C contributes to normal collagen formation for the normal function of blood vessels and the protection of cells from oxidative stress.
Micronized diosmin, dry extract of Centella leaves (Centella asiatica (L), 20% titre in total triterpenes, Micronized Hesperidin, Bulking agents: microcrystalline cellulose, Maltodextrin; dry extract of red vine seeds (Vitis Vinifera L.) tit 95% in proanthocyanidins; Stabilizer: Polyvinylpyrrolidone; Vitamin C (L-ascorbic acid), dry extract of bilberry fruits (Vaccinium Myrtillus L.) tit. 1% in anthocyanins, micronized Quercetin, micronized Rutin, anti-caking agents: magnesium stearate, silicon dioxide.
It is recommended to take 1 to 2 tablets a day with a glass of water.
Ingredients Daily dose (1 tablet) %NRV
Diosmin 225mg -
Hesperidin 135mg -
Rutin 65mg -
Quercetin 70mg -
Centella Asiatica
Triterpenes
150mg
30mg
-
Red Vine leaf
Proanthocyanins
100mg
95mg
-
Bilberry
Anthocyanins
80mg
0,8mg
-
Vitamin C 160mg 100
Bromelain 2500 GDU/mg 300mg -
Papain 100 TU/mg 200mg -
Zinc 10mg 100

NRV= daily Nutrient Reference Values (Reg. EU n. 1169/2011)

Ingredients Maximum Daily intake (2 tablets) %NRV
Micronized Diosmin 450mg -
Centella Asiatica
Triterpenes
300mg
60mg
-
Micronized Hesperidin 270mg -
Red Vine leaf
Proanthocyanidins
200mg
190mg
-
Vitamin C 160mg 200%
Bilberry
Anthocyanins
160mg
1,6mg
-
Micronized Quercetin 140mg -
Micronized Rutin 130mg -
Dietary supplements are not intended as a substitute for a varied, balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of reach of children under 3 years. Do not take in case of hypersensitivity or allergies to one or more components. During pregnancy and breastfeeding ask your Doctor for advice.
Store at a temperature not exceeding 25-30 ° C, away from light and / or heat sources. The minimum storage term refers to the product properly stored in unopened package.

Flavofort 1500® is a food supplement based on micronized Flavonoids, Plant Extracts and Vitamin C useful in case of reduced intake or increased need for these nutrients. Blackberry, Centella and Red grapevine are useful for the microcirculation function, reducing the feeling of heaviness in the legs. Vitamin C contributes to normal collagen formation for the normal function of blood vessels and the protection of cells from oxidative stress.

Micronized diosmin, dry extract of Centella leaves (Centella asiatica (L), 20% titre in total triterpenes, Micronized Hesperidin, Bulking agents: microcrystalline cellulose, Maltodextrin; dry extract of red vine seeds (Vitis Vinifera L.) tit 95% in proanthocyanidins; Stabilizer: Polyvinylpyrrolidone; Vitamin C (L-ascorbic acid), dry extract of bilberry fruits (Vaccinium Myrtillus L.) tit. 1% in anthocyanins, micronized Quercetin, micronized Rutin, anti-caking agents: magnesium stearate, silicon dioxide.

It is recommended to take 1 to 2 tablets a day with a glass of water.

Ingredients Daily dose (1 tablet) %NRV
Diosmin 225mg -
Hesperidin 135mg -
Rutin 65mg -
Quercetin 70mg -
Centella Asiatica
Triterpenes
150mg
30mg
-
Red Vine leaf
Proanthocyanins
100mg
95mg
-
Bilberry
Anthocyanins
80mg
0,8mg
-
Vitamin C 160mg 100
Bromelain 2500 GDU/mg 300mg -
Papain 100 TU/mg 200mg -
Zinc 10mg 100

NRV= daily Nutrient Reference Values (Reg. EU n. 1169/2011)

Ingredients Maximum Daily intake (2 tablets) %NRV
Micronized Diosmin 450mg -
Centella Asiatica
Triterpenes
300mg
60mg
-
Micronized Hesperidin 270mg -
Red Vine leaf
Proanthocyanidins
200mg
190mg
-
Vitamin C 160mg 200%
Bilberry
Anthocyanins
160mg
1,6mg
-
Micronized Quercetin 140mg -
Micronized Rutin 130mg -

productwarning

Store at a temperature not exceeding 25-30 ° C, away from light and / or heat sources. The minimum storage term refers to the product properly stored in unopened package.
Made in Italy
Made in Italy
Gluten Free
Gluten Free
Lactose free
Lactose free

Scientific evidences on actives

  • Romano A. et al. A topical combination of blackberry, Centella asiatica, sodium hyaluronate, vitamin E and Melilotus to relieve legs symptoms of venous insufficiency Veins&Lymph 2020, 9(1), pp. 15-17.
  • Cesarone M.R. et al. Microcirculatory effects of total triterpenic fraction of Centella asiatica in chronic venous hypertension: measurement by laser Doppler, TcPO2-CO2, and leg volumetry. Angiology 52 Suppl 2:S45-48, 2001.
  • Aguilar-Peralta G.R. et al. Clinical and capillaroscopic evaluation in the treatment of chronic venous insufficiency with Ruscus aculeatus, hesperidin methylchalcone and ascorbic acid in venous insufficiency treatment of ambulatory patients. Int Angiol. 26(4):378-384, 2007.
  • Rabe et al. Eur J Vasc Endovasc Surg (2011) 41, 540e547.
  • Marco Basile, Stefano Gidaro, Massimo Pacella, Paolo M. Biffignandi and Giacomo S. Gidaro Parenteral Troxerutin and Carbazochrome Combination in the Treatment of Posthemorrhoidectomy Status: A Randomized, Double blind, Placebo-controlled, Phase IV Study Current Medical Research And Opinion Vol. 17, No. 4, 2001, 256-261.
  • Y.-H. Ho, C.L. Foo, F. Seow-Choen and H.S. GOH Prospective randomized controlled trial of a micronized flavonidic fraction to reduce bleeding after haemorrhoidectomy British Journal of Surgery 1995, 82, 1034-1035.
  • Galley P., Thiolet M.: A double-blind, placebocontrolled trial of a new veno-active fraction (S5682) in the treatment of symptomatic capillary fragility. Int Angiol 1993;12:69-72.
  • Cesarone M.R., Belcaro G., Pellegrini L., Ledda A., Di Renzo A., Vinciguerra G., Ricci A., Gizzi G., Ippolito E., Fano F., Dugall M., Acerbi G., Cacchio M. H.R., 0-(betahydroxyethyl)- rutosides, in comparison with diosmin+hesperidin in chronic venous insufficiency and venous microangiopathy: an independent, prospective, comparative registry study. Angiology. 2005 Jan-Feb;56(1):1-8.
  • Kiesewetter H., Koscielny J., Kalus U., Vix J.M., Peil H., Petrini O., van Toor B.S., de Mey C. Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I-II). A randomized, double-blind, placebo-controlled trial. Arzneimittelforschung. 2000 Feb;50(2):109-17.
  • Greeske K., Pohlmann B.K. Rosskastaniensamenextrakt-ein wirksames Therapieprinzip in der Praxis. Fortschr Med 1996; 114:196-200.
  • Martinez-Zapata MJ, Vernooij RWM, Uriona Tuma SM, Stein AT, Moreno RM, Vargas E, Capellà D, Bonfill Cosp X. Phlebotonics for venous insufficiency. Cochrane Database Syst Rev. 2016 Apr 6;4:CD003229. doi: 10.1002/14651858.CD003229.pub3. Review.
  • Widmer LK. Pheripheral venous disorders: prevalence and socio-medical importance. Hans Huber, Bern 1978.
  • Amisano GC, Amisano MF. Flebologia, da ieri al domani. L’insufficienza venosa ed una sua complicanza: “l’ulcera”. Casa di Cura Salus, Alessandria.
  • Scortecci V. Chirurgia generale - Patologia chirurgica per apparati. Raffaello Cortina Editore. Milano, 1996.
  • Garreu C, Garreu Gomez B, Domenjou JM, Bianchi D, Portail M. Venous insufficiency and varicouse disease. Sequelae of lower limb thrombosis. The role of crenotherapy. Phlebologie, 1993 Apr, Jun 46 (2):303-11.
  • Nyuk Jet Chong and Zoriah Aziz. A Systematic Review of the Efficacy of Centella asiatica for Improvement of the Signs and Symptoms of Chronic Venous Insufficiency. Evidence-Based Complementary and Alternative Medicine Volume 2013, Article ID 627182, 10 pages http://dx.doi. org/10.1155/2013/627182.
  • Ulbricht et al. An Evidence-Based Systematic Review of Bilberry (Vaccinium myrtillus) by the Natural Standard Research Collaboration. Journal of Dietary Supplements, Vol. 6(2), 2009.
  • Assessment report for the development of community monographs and for inclusion of herbal substance(s), preparation (s) or combinations thereof in the list.
  • Merita F., Se le vene delle gambe soffrono, su Sapere&Salute, anno 4, num. 21, luglio 1999, pagg. 48-50.
  • Pigozzi P., Causa, prevenzione e cure naturali delle vene varicose, Demetra.
  • Rosellò R., Curare le gambe stanche e le varici con trattamenti naturali, Macro Edizioni.
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